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Updated: Feb 16, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.7K

An updated review of pediatric drug-induced sleep endoscopy

Lyndy J Wilcox1, Mathieu Bergeron1, Saranya Reghunathan2

  • 1Division of Pediatric Otolaryngology-Head and Neck Surgery Cincinnati Children's Hospital Medical Center Cincinnati Ohio U.S.A.

Laryngoscope Investigative Otolaryngology
|January 5, 2018
PubMed

Insights

Drug-induced sleep endoscopy (DISE) is a safe method for evaluating pediatric obstructive sleep apnea (OSA). Standardized protocols and scoring systems are needed to improve consistency and surgical outcomes in children.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Anesthesiology

Background:

  • Obstructive sleep apnea (OSA) is a common condition in children.
  • Drug-induced sleep endoscopy (DISE) is a diagnostic tool used to assess upper airway obstruction during sleep.
  • Understanding the role of DISE in pediatric OSA is crucial for effective management.

Purpose of the Study:

  • To review the current literature on the use of DISE in children with OSA.
  • To discuss indications, anesthetic protocols, diagnostic comparisons, scoring systems, and outcomes of pediatric DISE.

Main Methods:

  • A comprehensive literature review was performed.
  • Literature search focused on pediatric DISE up to May 2017.

Main Results:

  • DISE effectively evaluates airway obstruction sites during sedation.
  • Indications include persistent OSA post-tonsillectomy, OSA without tonsillar hypertrophy, and suspected sleep-state dependent laryngomalacia.
  • Dexmedetomidine/ketamine protocols are safe for pediatric DISE; propofol is common in adults.
  • Six scoring systems exist, but none are universally accepted.

Conclusions:

  • DISE is a safe and valuable technique for assessing pediatric airway obstruction.
  • Lack of standardized anesthetic protocols and scoring systems hinders consistent reporting and communication.
  • Development of universal standards is necessary for optimizing surgical outcomes in pediatric OSA.
Abstract

Keywords:
DISEdrug‐induced sleep endoscopyobstructive sleep apneapediatric

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