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Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment.

Ibrahim A Abdel-Hamid¹, Omar I Ali²

¹Division of Andrology, Mansoura Faculty of Medicine, Mansoura, Egypt. ibrahamid2007@yahoo.com.

The World Journal of Men'S Health

|January 5, 2018

Summary

This summary is machine-generated.

Delayed ejaculation (DE) and anejaculation (AE) are male sexual dysfunctions with unknown causes. Treatment for DE/AE is cause-specific, with options including psychological interventions and therapies for infertility.

Keywords:

Anejaculation Delayed ejaculation Diagnosis Physiopathology Therapy

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Area of Science:

Male Sexual Dysfunction
Reproductive Medicine
Urology

Background:

Delayed ejaculation (DE) and anejaculation (AE) are uncommon male sexual dysfunctions.
These conditions cause significant distress to patients and partners, impacting fertility.
The pathophysiology remains incompletely understood, with multifactorial causes.

Purpose of the Study:

To review the pathophysiology of DE and AE.
To explore current diagnostic approaches.
To present available treatment options.

Main Methods:

Comprehensive literature search of electronic databases (PubMed, Embase) from 1966 to October 2017.
Combined MeSH terms/keywords related to DE/AE with epidemiological, etiological, diagnostic, and treatment concepts.
Reviewed relevant sexual medicine textbooks.

Main Results:

DE/AE pathophysiology is multifactorial, involving organic and psychosocial elements, though exact pathogenesis is unknown.
No gold standard exists for DE/AE diagnosis; clinical history is crucial.
Treatment is cause-specific, with psychological interventions, pharmacotherapy (no approved drugs), and fertility treatments available.

Conclusions:

DE/AE are complex conditions requiring individualized, cause-specific treatment.
Further research is needed to elucidate pathogenesis and establish diagnostic standards.
A range of interventions exist for infertile men experiencing DE/AE.