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There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
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Knowledge of anatomy is essential to understand human biology and medicine. Anatomists and health care professionals use standard terminology to describe the human body with more precision and no ambiguity. Anatomical terms have mostly Greek and Latin-derived roots. Because these languages are rarely used in conversation, the meaning of words remains the same. Each term is made up of a root in between the prefixes and suffixes. The root of a term often refers to an organ, tissue, or condition,...
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Related Experiment Video

Updated: Feb 16, 2026

3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
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D-Shaped Left Ventricle, Anatomic, and Physiologic Implications.

Eder Hans Cativo Calderon1, Tuoyo O Mene-Afejuku1, Rachna Valvani1

  • 1Department of Medicine, New York Medical College, Metropolitan Hospital Center, Valhalla, NY, USA.

Case Reports in Cardiology
|January 6, 2018
PubMed
Summary
This summary is machine-generated.

Right ventricular pressure overload can cause a D-shaped left ventricle, impacting cardiac function. This case highlights the importance of recognizing this condition in patients with shortness of breath.

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Area of Science:

  • Cardiology
  • Cardiac Physiology
  • Echocardiography

Background:

  • The left and right ventricles influence each other's function due to their serial pumping and parallel anatomical arrangement.
  • Interventricular septum deviation can alter ventricular geometry and cardiac output.

Observation:

  • An elderly male presented with shortness of breath and was diagnosed with a D-shaped left ventricle via echocardiogram.
  • This cardiac morphology was secondary to right ventricular volume/pressure overload.

Findings:

  • Hemodialysis led to paradoxical blood pressure increase during volume removal.
  • Serial echocardiograms showed reduced interventricular septum deviation after volume management.

Implications:

  • Physicians should understand the anatomical and physiological effects of right ventricular overload on left ventricular function.
  • Recognizing D-shaped left ventricle is crucial for managing complex cardiac conditions.