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Updated: Feb 16, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Echocardiographic evaluation and guidance for MitraClip procedure
William E Katz1, Anson J Conrad Smith1, Frederick W Crock1
1Division of Cardiovascular Diseases, Department of Medicine, UPMC Heart & Vascular Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Transcatheter mitral valve repair with the MitraClip system is a proven treatment for severe mitral regurgitation in high-risk patients. This review details patient selection, imaging, and procedural guidance for optimal outcomes.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Imaging
Background:
- Transcatheter mitral valve repair (TMVR) using the MitraClip system is a key therapy for severe mitral regurgitation (MR).
- It is indicated for symptomatic patients with prohibitive surgical risk.
- The MitraClip system offers a less invasive alternative to conventional surgery.
Purpose of the Study:
- To provide a comprehensive review of clinical and imaging aspects for MitraClip therapy.
- To guide patient selection, imaging evaluation, and intraprocedural techniques.
- To offer an updated framework based on current literature and clinical experience.
Main Methods:
- Literature review of clinical studies and imaging techniques for MitraClip.
- Analysis of patient selection criteria for TMVR.
- Evaluation of echocardiographic and other imaging modalities for procedural guidance.
Main Results:
- The MitraClip system is a well-established, worldwide therapeutic option.
- Optimal patient selection and imaging are crucial for successful outcomes.
- Experienced practitioners can achieve excellent results with this device.
Conclusions:
- MitraClip therapy is a valuable tool for managing severe mitral regurgitation in high-risk patients.
- A thorough understanding of clinical and imaging parameters enhances procedural success.
- This review provides a current framework for practitioners utilizing this transcatheter approach.
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