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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
[Extracorporeal life support in calcium antagonist intoxication]
M W Groot1, S Grewal, H J Meeder
1Erasmus MC, afd. Intensive Care Volwassenen, Rotterdam.
Background:
Intoxication with calcium antagonists is associated with poor outcome. Even mild calcium antagonist overdose may be fatal.
Case Description:
A 51-year-old woman and a 51-year-old man came to the Accident and Emergency Department in severe shock after they had taken a calcium antagonist overdose. After extensive medicinal therapy had failed, they both needed extracorporeal life support (ECLS) as a bridge to recovery.
Conclusion:
In severe calcium antagonist overdose, the combination of vasoplegia and cardiac failure leads to refractory shock. ECLS temporarily supports the circulation and maintains organ perfusion. In this way ECLS functions as a bridge to recovery and may possibly save lives. Timely consultation with and referral to an ECLS centre is recommended in patients with calcium antagonist overdose.
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