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Comparison of calf muscle architecture between Asian children with spastic cerebral palsy and typically developing
Ying Chen1, Lu He1, Kaishou Xu1
1Department of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Insights
Children with spastic cerebral palsy (CP) show reduced muscle thickness and fascicle length in key leg muscles compared to typically developing peers. These muscle architecture changes in CP may impact mobility and suggest a need for targeted strengthening interventions.
Area of Science:
- Neurology
- Pediatrics
- Biomedical Engineering
Background:
- Spastic cerebral palsy (CP) is a common childhood motor disorder.
- Muscle architecture alterations may contribute to functional limitations in children with CP.
Purpose of the Study:
- To compare muscle thickness, fascicle length, and pennation angle of the gastrocnemius, soleus, and tibialis anterior muscles.
- To investigate differences between Asian children with spastic CP and typically developing (TD) peers.
Main Methods:
- Cross-sectional study of 72 children (24 hemiplegic CP, 24 diplegic CP, 24 TD peers).
- Ultrasound measurements of muscle architecture at rest.
- Clinical assessments included gross motor function and modified Ashworth scale.
Main Results:
- Children with CP exhibited smaller tibialis anterior and medial gastrocnemius muscle thicknesses.
- Shorter fascicle lengths were observed in the lateral gastrocnemius and soleus muscles of children with diplegic CP and in the affected calf of children with CP.
- Larger pennation angles were found in the medial gastrocnemius and soleus muscles of children with hemiplegic CP.
- Positive correlations were noted between lateral gastrocnemius fascicle length, soleus muscle thickness, and gross motor function scores in children with CP.
Conclusions:
- Children with spastic CP have reduced muscle thickness and fascicle length in the tibialis anterior, gastrocnemius, and soleus muscles.
- These findings suggest potential limitations in standing and walking abilities.
- Interventions to strengthen affected muscles are indicated.
Objective:
To compare the muscle thickness, fascicle length, and pennation angle of the gastrocnemius, soleus, and tibialis anterior between Asian children with spastic cerebral palsy (CP) and typically developing (TD) peers.
Methods:
This cross-sectional study involved a total of 72 children with hemiplegic CP (n = 24), and diplegic CP (n = 24) and their TD peers (n = 24). Muscle architecture was measured at rest using ultrasound. Clinical measures included gross motor function and a modified Ashworth scale.
Results:
The thicknesses of the tibialis anterior and medial gastrocnemius muscles were smaller in the affected calf of children with CP (p<0.05) than in those of their TD peers. Additionally, the lengths of the lateral gastrocnemius and soleus fascicle were shorter (p<0.05) in children with diplegic CP than in their TD peers. The fascicle length was shorter in the affected calf of children with CP (p<0.05) than in the calves of their TD peers or the unaffected calf of children with hemiplegic CP. However, the length of the lateral gastrocnemius fascicle was similar between the two legs of children with hemiplegic CP. The pennation angles of the medial gastrocnemius and soleus muscles were larger (p<0.05) in the affected calf in children with hemiplegic CP than in the calves of their TD peers. The fascicle length of the lateral gastrocnemius and the thickness of the soleus muscle were positively correlated with gross motor function scores in children with CP (p<0.05).
Conclusions:
Muscle thickness and fascicle length were lower in the affected tibialis anterior, gastrocnemius, and soleus in children with spastic CP. These changes may limit the ability to stand and walk, and indicate a need to strengthen the affected muscle.
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