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Fluorescence-Quenched Substrates for Quantitative Live Cell Imaging of Glucocerebrosidase Activity

Roger A Ashmus1, David L Shen1, David J Vocadlo1

  • 1Simon Fraser University, Burnaby, BC, Canada.

Methods in Enzymology
|January 8, 2018
PubMed

Keywords:
FRET-based (dark-to-light) substrateGaucher's diseaseGlucocerebrosidaseGlucosylceramideGlycolipidGlycoside hydrolaseLive cell imaging substrateLysosomal enzymeParkinson's disease

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