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Traits, Mood, and Subjective Wellbeing

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Subjective well-being (SWB) refers to an individual's self-evaluation of their overall life satisfaction, happiness, and fulfillment. This multifaceted construct is typically assessed by analyzing the balance of positive and negative emotions alongside perceptions of life satisfaction. Personality traits such as neuroticism and extraversion are strongly associated with variations in SWB, offering critical insights into the underlying mechanisms of emotional well-being.
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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
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Behavior Therapy01:22

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Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
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Drug Therapy01:28

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Ole Isacson: Development of New Therapies for Parkinson's Disease
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Mood changes with methotrexate therapy for dermatologic disease.

Trisha Bhat1, Carrie C Coughlin2

  • 1School of Medicine, Washington University, St. Louis, MO, USA.

Pediatric Dermatology
|January 10, 2018
PubMed
Summary

Low-dose methotrexate can cause mood changes in children with skin conditions. These neuropsychiatric effects resolved quickly after stopping the medication, highlighting a need for awareness in dermatology.

Area of Science:

  • Dermatology
  • Neuropsychiatry
  • Pediatrics

Background:

  • Neurotoxicity and cognitive effects of low-dose methotrexate are known in rheumatologic conditions.
  • Neuropsychiatric effects of low-dose methotrexate for cutaneous diseases are underreported in dermatology literature.
Keywords:
drug reactioninflammatory disorderspharmacologypsoriasissystemictherapy

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