High-Density Mapping in Ventricular Tachycardia Ablation: A PentaRay® Study.
Petra Maagh1, Arnd Christoph1, Henning Dopp1
1Department of Cardiology, Electrophysiology and Intensive Care, Klinikum Merheim, University Witten/Herdecke/Germany, Ostmerheimer Str. 200, 51109 Cologne, Germany.
Cardiology Research
|January 11, 2018
Summary
High-density mapping of ventricular tachycardia (VT) using PentaRay® is feasible for characterizing anatomical substrates. Medium-term outcomes show promising results for arrhythmia recurrence-free survival in VT patients.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- High-density mapping of ventricular tachycardia (VT) with PentaRay® offers high resolution for identifying abnormal electrograms and slow conducting channels.
- This study evaluates the feasibility of using PentaRay® to characterize the anatomical substrate of VT.
Purpose of the Study:
- To assess the feasibility of high-density mapping with PentaRay® for characterizing VT anatomical substrates.
- To evaluate the influence of PentaRay® mapping on VT catheter ablation outcomes.
Main Methods:
- 26 endocardial and 4 epicardial maps were created in 26 VT patients (18 ischemic cardiomyopathy, 8 non-ischemic cardiomyopathy) over 24 months.
- Catheter ablation (CA) aimed at isthmus transection, with non-inducibility of VT as the endpoint.
- Manual map review focused on scarring, bipolar electrograms, and procedure times.
Main Results:
- High-density maps were created in an average of 55.6 minutes, with 1,085.9 points per map.
- The VT non-inducibility endpoint was achieved in 46.2% of patients.
- At a 14-month follow-up, 65.4% of patients remained free from arrhythmia recurrence.
Conclusions:
- PentaRay® enabled safe and rapid creation of high-density maps for VT.
- Despite limitations in current annotation criteria, medium-term outcomes were encouraging.
- Further prospective studies are needed to validate these findings in a larger patient cohort.
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