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Cancer-Critical Genes I: Proto-oncogenes

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Updated: Feb 15, 2026

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

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Published on: April 11, 2025

Oncogenic osteomalacia

A K Annamalai¹, A J Gill², A Shinto³

¹Department of Endocrinology, Ashwin Speciality Hospital, Madurai, Tamil Nadu, India.

QJM : Monthly Journal of the Association of Physicians

|January 11, 2018

Summary

No abstract available in PubMed .

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