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Updated: Feb 15, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
A case of pulmonary cyst and pneumothorax after bronchial thermoplasty
Akifumi Funatsu1, Konomi Kobayashi1,2, Motoyasu Iikura1
1Department of Respiratory Medicine National Center for Global Health and Medicine Tokyo Japan.
Abstract:
Bronchial thermoplasty (BT) is a bronchoscopic treatment for severe asthma using thermal energy to reduce smooth muscle in the bronchial wall. A 47-year-old man underwent BT for uncontrolled severe asthma despite maximal pharmacological treatment. After a third procedure, he experienced hypoxaemia because of complete bilateral upper lobe atelectasis. A pulmonary cyst suddenly emerged in to the right middle lobe, associated with the pneumothorax on postoperative day 6, and a chest drainage tube was inserted. As atelectasis of the right upper lung suddenly improved on postoperative day 12, pneumothorax and the cyst improved. Excess stress on the middle lobe due to upper lobe collapse, and check valve due to airway oedema and phlegm, might be related to pulmonary cyst formation. Tissue fragility related to systemic steroid usage and pressure load during pulmonary function testing might influence the occurrence of pneumothorax. Severe adverse events under complete atelectasis after BT require careful attention.
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