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A Modified Co-Culture System for Understanding Granulosa-Theca Cell Interactions in the Bovine Ovary
Published on: September 19, 2025
An elderly woman with a mediastinal granulosa cell tumour: a rare presentation
Garrett M Harp1, Gregory N Matwiyoff1, Steven J Escobar1
1Department of Pulmonary Medicine Naval Medical Center San Diego San Diego CA USA.
Abstract:
Mediastinal lesions occur in a wide variety of clinical conditions. Metastatic granulosa cell tumour (GCT) in the mediastinum is a rare occurrence. We report a case of a woman who had a metastatic (GCT) in her mediastinum 40 years after treatment of the initial neoplasm. Surgical resection of the mediastinal mass revealed a low-grade epithelioid neoplasm with coffee bean-shaped nuclei and immunohistochemical stains that were consistent with metastatic GCT.
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