Chronicity, crisis, and the 'end of AIDS'

Thurka Sangaramoorthy1

  • 1a Department of Anthropology , University of Maryland , College Park , USA.

Global Public Health
|January 12, 2018
PubMed

Insights

The concept of an "end of AIDS" through HIV chronicity overlooks ongoing crises. This perspective, driven by treatment advances, prolongs uncertainty and social precarity, especially for marginalized communities.

Area of Science:

  • Public Health
  • Medical Anthropology
  • Sociology of Health

Background:

  • The discourse of an 'end of AIDS' is prevalent in public health and biomedical fields.
  • This narrative frames HIV as a manageable chronic condition, emphasizing lifelong treatment.
  • This approach is influenced by advancements in HIV treatment and global health investments.

Purpose of the Study:

  • To critically examine the concept of HIV chronicity and its role in the 'end of AIDS' discourse.
  • To explore how HIV chronicity intensifies long-term uncertainty and prolonged crisis.
  • To analyze how this discourse obscures the ongoing HIV crisis, particularly for marginalized and aging populations.

Main Methods:

  • Long-term (10+ years) ethnographic research and public health investigation in the United States.
  • Analysis of discourse surrounding HIV chronicity and the 'end of AIDS' in field sites and global contexts.

Main Results:

  • HIV chronicity, while a result of medical progress, perpetuates long-term uncertainty and crisis.
  • The 'end of AIDS' discourse, built on HIV chronicity, masks the persistent HIV crisis.
  • Marginalized and aging populations in under-resourced areas are disproportionately affected, experiencing ongoing social precarity.

Conclusions:

  • HIV chronicity signifies a continuing global crisis and social precarity, not an end to AIDS.
  • The 'end of AIDS' narrative obscures the lived realities of those experiencing the ongoing HIV epidemic.
  • Rethinking HIV management requires addressing the social determinants and persistent inequalities faced by affected communities.

Related Concept Videos

Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...