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Related Concept Videos

¹H NMR of Conformationally Flexible Molecules: Temporal Resolution00:52

¹H NMR of Conformationally Flexible Molecules: Temporal Resolution

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At room temperature, the chair conformer of cyclohexane undergoes rapid ring flipping between two equivalent chair conformers at a rate of approximately 105 times per second. These two chair conformers are in equilibrium. The rapid ring flipping results in the interconversion of the axial proton to an equatorial proton and an equatorial to the axial proton. Such interconversions are too rapid and cannot be detected on the NMR timescale. Hence, the NMR spectrometer cannot distinguish between the...
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¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR01:15

¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR

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The axial and equatorial protons in cyclohexane can be distinguished by performing a variable-temperature NMR experiment. In this process, except for one proton, the remaining eleven protons are replaced by deuterium. The deuterium substitution avoids the possible peak splitting caused by the spin-spin coupling between the adjacent protons. The remaining proton flips between the axial and equatorial positions.
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Lewis Acids and Bases02:33

Lewis Acids and Bases

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In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
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Weak Base Solutions03:21

Weak Base Solutions

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Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
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Base Excision Repair01:54

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One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
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Ions as Acids and Bases02:54

Ions as Acids and Bases

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Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
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Bioinspired Soft Robot with Incorporated Microelectrodes
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Bioinspired Universal Flexible Elastomer-Based Microchannels.

Feng Wu1, Songyue Chen2, Baiyi Chen3

  • 1Bionic and Soft Matter Research Institute, College of Physical Science and Technology, Xiamen University, 361005, Xiamen, China.

Small (Weinheim an Der Bergstrasse, Germany)
|January 12, 2018
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Summary
This summary is machine-generated.

Researchers developed a universal strategy for stable, stretchable microfluidic devices. These flexible microchannels offer dynamic liquid transport for wearable electronics and biomedical applications.

Keywords:
bioinspired deviceselastomersflexible microchannels

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Area of Science:

  • Materials Science
  • Microfluidics
  • Mechanical Engineering

Background:

  • Flexible and stretchable microfluidic devices are crucial for wearable electronics and biomedical applications.
  • Current fabrication methods and material limitations hinder the development of stable, dynamic microfluidic channels.
  • Elastomeric microchannels often face challenges in achieving both stability and stretchability.

Purpose of the Study:

  • To present a universal strategy for fabricating highly stable and stretchable microfluidic devices.
  • To demonstrate the mechanical properties and diverse applications of the developed microfluidic devices.
  • To explore the integration of various materials and surface modifications for enhanced functionality.

Main Methods:

  • Development of a novel fabrication strategy for microfluidic devices.
  • Characterization of mechanical properties, including high strain (967%) and recovery ability.
  • Integration of organic, inorganic, and metallic materials to create composite microfluidics.
  • Surface chemical modification to impart antifouling properties.

Main Results:

  • The developed microfluidic devices exhibit exceptional stability and stretchability.
  • Demonstrated applications include use as strain sensors and pressure-flow regulating devices.
  • Composite microfluidics incorporating diverse materials were successfully created.
  • Surface modification resulted in antifouling properties, broadening application scope.

Conclusions:

  • The universal strategy enables the creation of robust, flexible, and stretchable microfluidic devices.
  • These devices show significant potential in advanced wearable electronics and biomedical engineering.
  • The ability to integrate various materials and functionalities enhances their versatility for industrial and medical uses.