The Casper Stent System for carotid artery stenosis

Area of Science:

• Vascular Surgery
• Interventional Cardiology
• Neurology

Background:

• Carotid artery occlusive disease poses a significant risk of stroke.
• Stenting is a common intervention for carotid artery stenosis.
• Novel stent designs are continuously being developed to improve safety and efficacy.

Purpose of the Study:

• To evaluate the safety and efficacy of the Casper double-layer stent for carotid artery occlusive disease.
• To analyze outcomes of patients treated with the Casper stent using prospectively collected data.

Main Methods:

• Retrospective analysis of prospectively collected data from 138 patients (January 2014 - February 2017).
• Patients underwent Casper stent implantation for significant carotid artery stenosis (>70% or >50% with ulceration).
• A distal embolic protection device was used in all procedures; primary endpoint was 90-day major adverse neurological events.

Main Results:

• Successful stent deployment in all patients with no technical failures.
• Zero major adverse neurological events or deaths within the 90-day follow-up period.
• One case of thromboembolic occlusion resolved with treatment; 6.5% of patients had silent ischemic lesions on MRI.

Conclusions:

• The Casper carotid stent is safe and effective for treating carotid stenosis.
• The double-layer design offers a balance of plaque scaffolding and vessel adaptability.
• No adverse neurological events or technical failures were observed during the 90-day follow-up.