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Updated: Feb 15, 2026
09:13
Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
Published on: June 14, 2017
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Developing a mitral valve center of excellence
Current Opinion in Cardiology
|January 13, 2018
Summary
Establishing mitral valve centers of excellence is crucial for improving patient outcomes. This review defines the structure and achievable clinical results for these specialized centers, emphasizing mitral repair over replacement.
Area of Science:
- Cardiovascular Surgery
- Valvular Heart Disease
- Medical Guidelines
Background:
- Mitral valve repair is superior to replacement for degenerative mitral disease, yet replacement is frequently performed.
- Guidelines recommend referral to specialized valve centers, but criteria remain undefined.
- Centers of excellence are vital for achieving optimal mitral valve surgery outcomes.
Purpose of the Study:
- To define the structural components of a mitral center of excellence.
- To review the clinical outcomes achievable in such specialized centers.
- To provide a framework for establishing high-performing mitral valve reference centers.
Main Methods:
- Review of current American College of Cardiology/American Heart Association and European Society of Cardiology/European Association of Cardiothoracic Surgery guidelines.
- Analysis of established criteria for mitral centers of excellence.
- Synthesis of clinical outcomes data from high-volume mitral valve surgery centers.
Main Results:
- Mitral centers of excellence are defined by high rates of successful and durable mitral repair (>95%) and low operative mortality (<1%).
- Key components include specialized surgical teams, advanced technology, and robust patient selection protocols.
- Achievable outcomes include superior long-term durability and reduced morbidity compared to general cardiac surgery centers.
Conclusions:
- Mitral valve surgery outcomes are significantly improved at specialized centers of excellence.
- Defining the structure and function of these centers is essential for guideline implementation.
- Referral to established mitral centers of excellence should be prioritized for patients with degenerative mitral disease.
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