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Related Experiment Video

Updated: Feb 15, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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Polydioxanone Versus Polypropylene Closure For Midline Abdominal Incisions.

Samina Naz1, Sohail Ahmed Memon2, Mansoor Ali Jamali3

  • 1Department of Surgery, Federal Government Services Hospital, Islamabad, Pakistan.

Journal of Ayub Medical College, Abbottabad : JAMC
|January 14, 2018
PubMed
Summary

Polydioxanone sutures significantly reduce postoperative wound pain and infection rates following midline abdominal closure compared to Polypropylene sutures. This finding offers a better option for surgical wound management.

Keywords:
Abdominal wound closureMidline laparotomyWound infectionWound pain

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Area of Science:

  • Surgical techniques
  • Wound healing
  • Sutures and wound closure

Background:

  • Midline laparotomy is a common abdominal incision technique.
  • Abdominal fascia closure after midline laparotomy presents challenges.
  • Evaluating suture materials for midline closure is crucial for patient outcomes.

Purpose of the Study:

  • To compare Polydioxanone and Polypropylene sutures for midline abdominal fascia closure.
  • To assess the impact of suture material on postoperative wound infection.
  • To evaluate the effect of suture material on postoperative wound pain.

Main Methods:

  • A comparative study involving 620 patients undergoing midline laparotomy.
  • Patients were divided into two groups for abdominal closure: Polydioxanone (Group A) and Polypropylene (Group B).
  • Postoperative wound pain was assessed using the Visual Analogue Scale (VAS), and wound infection rates were recorded.

Main Results:

  • Polydioxanone group showed lower rates of moderate to severe pain (36.7%) compared to Polypropylene (59.6%).
  • The incidence of wound infection was substantially lower in the Polydioxanone group (33.9%) versus the Polypropylene group (67.1%).
  • Polydioxanone demonstrated superior outcomes in reducing both pain and infection.

Conclusions:

  • Polydioxanone is associated with reduced postoperative wound pain compared to Polypropylene.
  • Polydioxanone sutures lead to a lower incidence of wound infection after midline abdominal closure.
  • Polydioxanone presents a favorable alternative for midline abdominal fascia closure.