Related Experiment Video For Cytokeratin

Updated: Feb 15, 2026

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression

Published on: March 17, 2020

Squamous Cell Carcinoma Lung with Skeletal Muscle Involvement: A 8-year Study of a Tertiary Care Hospital in Kashmir

Javvid Muzamil¹, Shumail Bashir², Faisal R Guru¹

¹Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology

|January 16, 2018

Abstract

Aims:

Lung cancer is the most common malignancy throughout the world. Nonsmall cell lung cancer (NSCLC) is the most common type, and squamous cell type is most common in India. Mostly, patients present with chest-related symptoms and signs. Isolated skeletal muscle metastasis (ISMM) is rarely seen. The aim was to see muscle metastasis and its prognosis.

Materials And Methods:

We are presenting our data of 8 years about this common malignancy with relation to muscle metastasis, either alone or with other system metastasis.

Results:

Muscle metastasis is seen 1.5% of patients, with male: female of 8:1. Overall median survival was 15 months and progression-free survival was 12 months.

Conclusion:

One peculiarity seen was ISMM with no pulmonary system and severe paraneoplastic hypercalcemia. Local therapy may be having an impact on overall survival in metachronous muscle involvement.

Keywords:

Cytokeratin isolated skeletal muscle metastasis nonsmall cell lung carcinoma overall survival parathyroid hormone-related peptide progression-free survival superior vena cava thyroid transcription factor

More Related Videos

Development of Compendium for Esophageal Squamous Cell Carcinoma

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

Related Concept Videos

Classification of Skeletal Muscle Fibers

Classification of Skeletal Muscle Fibers

Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...

Hospitals-II

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...

Overview of Skeletal Muscle

Overview of Skeletal Muscle

Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...

Relaxation of Skeletal Muscles

Relaxation of Skeletal Muscles

The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....

Disorders of the Skeletal Muscle

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

Naming Skeletal Muscles

Naming Skeletal Muscles

The naming of the approximately 700 muscles in the human body is based on a set of criteria designed to provide descriptive information about each muscle, making it easier to identify and remember them.
The key factors used in naming muscles include:

Keywords:

Cytokeratin isolated skeletal muscle metastasis nonsmall cell lung carcinoma overall survival parathyroid hormone-related peptide progression-free survival superior vena cava thyroid transcription factor

Articles linked to this work by shared authors, journal, and citation graph.

Prognostic Factors and Survival Outcomes in Pediatric Acute Lymphoblastic Leukemia: A Real-World Retrospective Cohort Study from a Tertiary Care Center in North India.

Cureus·2026

Non-cryopreserved Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma in a Resource-Limited Setting: Feasibility, Engraftment Kinetics, and Early Outcomes From Kashmir, India.

Cureus·2026

Shankh blowing in obstructive sleep apnoea: something special or a routine respiratory exercise?

ERJ open research·2026

Follicular dendritic cell sarcoma: a great mimicker with unpredictable clinical course-experience from a tertiary care cancer center in India.

Frontiers in oncology·2025

Prevalence of EGFR Mutations in Patients With Resected Stage I to III Nonsquamous Non-Small Cell Lung Cancer: Results of India Cohort.

JCO global oncology·2025

Efficacy and Safety Profile of Biosimilar Polyethylene Glycol (PEG)-Asparaginase (Asviia) in Patients With Acute Leukemia: A Retrospective Study From Kashmir.

Cureus·2024

See all related articles