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Updated: Feb 15, 2026

Procedure for Decellularization of Rat Livers in an Oscillating-pressure Perfusion Device
Published on: August 10, 2015
Cyclic Nonrespiratory Pulse Pressure Oscillations Caused by Atrioventricular Dissociation
László Rudas1, Péter Hankovszky1, András Lovas1
1Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Abstract:
Dynamic preload assessment tests, especially pulse pressure variation (PPV) and stroke volume variation (SVV), are increasingly acknowledged in mechanically ventilated patients as being predictors of fluid responsiveness. However, the limitations of this method are often neglected or overlooked. One of the prerequisites for PPV and SVV evaluation, in addition to intermittent positive pressure ventilation, is a "regular heart rhythm," which may be an ambiguous term. We present a case where, despite a regular (paced) rhythm, atrioventricular dissociation was present and resulted in marked PPV elevation, which subsequently disappeared once sinus rhythm returned. Our case indicates that PPV and SVV should be interpreted with caution when atrioventricular dissociation is present.
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