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Labial adhesions: Experience in a children's hospital

Anahí Rubinstein1, Gisel Rahman2, Paula Risso3

  • 1Unidad de Ginecología Infantojuvenil, Hospital de Niños Sor María Ludovica, La Plata, Provincia de Buenos Aires, República Argentina. vrubinstein@yahoo.com.ar.

Archivos Argentinos De Pediatria
|January 16, 2018
PubMed

Insights

Labial adhesions, a fusion of the labia minora, commonly affect young girls. Topical estrogen therapy effectively resolves most cases with minimal adverse events.

Area of Science:

  • Pediatric Gynecology
  • Dermatology
  • Urology

Background:

  • Labial adhesions involve the fusion of the labia minora, primarily affecting girls aged 3 months to 6 years.
  • This condition can range from partial to complete fusion of the pudendal cleft.
  • While often asymptomatic, it can be associated with urinary symptoms and urinary tract infections.

Purpose of the Study:

  • To analyze the presentation and treatment outcomes of labial adhesions in pediatric patients.
  • To determine the efficacy and safety of topical estrogen treatment for labial adhesions.

Main Methods:

  • Retrospective analysis of 425 girls diagnosed with labial adhesions between 2002 and 2015.
  • Data collected included patient age, severity of adhesions, presence of symptoms, and treatment outcomes.
  • Statistical analysis to identify common presentations and treatment efficacy.

Main Results:

  • The average age of affected girls was 2.7 years.
  • The most frequent presentation involved >75% of the labial length (p < 0.0000001).
  • 84.2% of patients were asymptomatic; 4% experienced urinary symptoms. 68.4% of girls with a history of UTI had >75% labial involvement.
  • Topical estrogen treatment resolved 90.6% of cases, with only 2.1% experiencing adverse events.

Conclusions:

  • Labial adhesions are common in young girls, often presenting as extensive fusion.
  • Topical estrogen is a highly effective and safe treatment for labial adhesions in this population.
  • Further investigation into the link between UTIs and severe labial adhesions may be warranted.

Keywords:
GirlsLabial adhesionsTreatment

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