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Vitamin D deficiency in pediatric clinical practice

Gustavo Cediel1, Johanna Pacheco-Acosta2, Carlos CastiUo-Durdn2

  • 1Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile. gcediel@inta.uchile.cl.

Archivos Argentinos De Pediatria
|January 16, 2018
PubMed

Insights

Vitamin D deficiency (VDD) is common in children with various health issues, including infections and autoimmune diseases. Preventing VDD and maintaining adequate vitamin D levels are crucial for pediatric health.

Area of Science:

  • Pediatric Endocrinology
  • Nutritional Science
  • Clinical Medicine

Background:

  • Emerging research indicates vitamin D's role extends beyond bone metabolism.
  • Vitamin D deficiency (VDD) is increasingly recognized in various pediatric conditions.

Purpose of the Study:

  • To provide an updated review of vitamin D deficiency (VDD) in pediatric clinical disorders.
  • To synthesize current evidence on the impact of VDD in children and adolescents.

Main Methods:

  • Comprehensive literature search of virtual libraries.
  • Prioritization of clinical, longitudinal studies, and meta-analyses.
  • Focused on the pediatric age group published within the last 20 years using specific search terms.

Main Results:

  • VDD in pediatrics is linked to bone alterations, insulin resistance, metabolic syndrome, respiratory infections, asthma, and autoimmune diseases.
  • Associated factors include prematurity, obesity, malabsorption, anticonvulsant use, and lifestyle factors like limited sun exposure.
  • High prevalence of VDD observed across multiple pediatric disorders.

Conclusions:

  • VDD is highly prevalent in various pediatric disorders and diseases.
  • Recommendations include VDD prevention in at-risk children.
  • Maintain serum 25(OH)D levels above 75 nmol/L for optimal pediatric health.
Abstract

Keywords:
ChildDeficiencyReviewVitamin D

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