Related Experiment Video
Updated: Feb 15, 2026

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
Published on: April 4, 2016
Plasma virome of cattle from forest region revealed diverse small circular ssDNA viral genomes
Hao Wang1,2, Shouxin Li3,4, Asif Mahmood1
1Department of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Background:
Free-range cattle are common in the Northeast China area, which have close contact with farmers and may carry virus threatening to cattle and farmers.
Methods:
Using viral metagenomics we analyzed the virome in plasma samples collected from 80 cattle from the forested region of Northeast China.
Results:
The virome of cattle plasma is composed of the viruses belonging to the families including Parvoviridae, Papillomaviridae, Picobirnaviridae, and divergent viral genomes showing sequence similarity to circular Rep-encoding single stranded (CRESS) DNA viruses. Five such CRESS-DNA genomes were full characterized, with Rep sequences related to circovirus and gemycircularvirus. Three bovine parvoviruses belonging to two different genera were also characterized.
Conclusion:
The virome in plasma samples of cattle from the forested region of Northeast China was revealed, which further characterized the diversity of viruses in cattle plasma.
Related Concept Videos
Size and Structure of Viral Genomes
Viral Recombination
Viral Structure
Genomics
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes
Cell Diversity
Multicellular...

