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Published on: March 2, 2018
Retrospective study of complete atrioventricular canal defects: Anesthetic and perioperative challenges
Aniruddha Ramesh Janai1, Wilfried Bellinghausen1, Edwin Turton1
1Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Leipzig, Germany.
Insights
Protocolized care for infants with complete atrioventricular canal defects significantly improves surgical outcomes. This approach ensures excellent results in biventricular repair surgery for these complex congenital heart conditions.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Surgery
- Anesthesiology
Background:
- Complete atrioventricular (AV) canal defects are complex congenital heart conditions requiring specialized surgical intervention.
- Infants with these defects often have associated comorbidities, such as Down syndrome, necessitating careful perioperative management.
Purpose of the Study:
- To evaluate the anesthetic and perioperative management strategies employed in infants undergoing surgical repair of complete atrioventricular canal defects.
- To assess the outcomes associated with a protocolized approach to biventricular repair in this patient population.
Main Methods:
- A retrospective descriptive study of 157 infants who underwent primary or staged biventricular repair for complete AV canal defects between 1999 and 2013.
- Data collected included demographic information, anesthetic management, cardiopulmonary bypass details, and intensive care unit (ICU) outcomes.
Main Results:
- A standardized protocol for anesthesia, cardiopulmonary bypass, and ICU care was consistently applied.
- Key outcomes included a 0% in-hospital mortality rate, a mean hospital stay of 14.5 days, and low rates of complications such as reoperation (3.8%) and permanent pacemaker implantation (2.5%).
- Pulmonary hypertension was present in 60% of patients, with 30% requiring nitric oxide therapy.
Conclusions:
- A protocolized perioperative management strategy is associated with excellent outcomes in infants undergoing surgical repair of complete atrioventricular canal defects.
- This standardized approach contributes to successful biventricular repair and improved patient survival.
Objective:
The objective of this study was to highlight anesthetic and perioperative management and the outcomes of infants with complete atrioventricular (AV) canal defects.
Design:
This retrospective descriptive study included children who underwent staged and primary biventricular repair for complete AV canal defects from 1999 to 2013.
Setting:
A single-center study at a university affiliated heart center.
Participants:
One hundred and fifty-seven patients with a mean age at surgery of 125 ± 56.9 days were included in the study. About 63.6% of them were diagnosed as Down syndrome. Mean body weight at surgery was 5.6 ± 6.3 kg.
Methods:
Primary and staged biventricular repair of complete AV canal defects.
Measurements And Main Results:
A predefined protocol including timing of surgery, management of induction and maintenance of anesthesia, cardiopulmonary bypass, and perioperative intensive care treatment was used throughout the study. Demographic data as well as intraoperative and perioperative Intensive Care Unit (ICU) data, such as length of stay in ICU, total duration of ventilation including reintubations, and total length of stay in hospital and in hospital mortality, were collected from the clinical information system. Pulmonary hypertension was noted in 60% of patients from which 30% needed nitric oxide therapy. Nearly 2.5% of patients needed permanent pacemaker implantation. Thorax was closed secondarily in 7% of patients. In 3.8% of patients, reoperations due to residual defects were undertaken. Duration of hospital stay was 14.5 ± 4.7 days. The in-hospital mortality was 0%.
Conclusion:
Protocolized perioperative management leads to excellent outcome in AV canal defect repair surgery.
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