Related Experiment Video
Updated: Feb 15, 2026

Electrocardiogram Recordings in Anesthetized Mice using Lead II
Published on: June 20, 2020
Detection of STEMI Using Prehospital Serial 12-Lead Electrocardiograms
Insights
Serial 12-lead electrocardiograms (ECGs) in ambulances helped identify ST-elevation myocardial infarction (STEMI) in 8% of patients initially showing no STEMI. This prehospital ECG monitoring improves STEMI detection during emergency medical services transport.
Area of Science:
- Cardiology
- Emergency Medicine
- Medical Technology
Background:
- Serial 12-lead electrocardiograms (ECGs) may enhance the management of ST-segment elevation (STE) or evolving ST-segment elevation myocardial infarction (STEMI) in prehospital settings.
- Limited scientific evidence currently supports the clinical utility of serial prehospital ECGs for STEMI detection.
Purpose of the Study:
- To evaluate the effectiveness of serial 12-lead ECGs in detecting STEMI among patients during transport by emergency medical services (EMS) in Canada.
Main Methods:
- A retrospective study analyzed suspected STEMI patients transported by EMS in Québec, Canada (August 2006 - December 2013).
- Patients underwent serial 12-lead ECG monitoring with transmission every 2 minutes.
- ECGs were reviewed by emergency physicians and categorized by persistent or dynamic STE.
Main Results:
- Of 728 eligible patients, 84.3% had persistent STE, and 15.7% had dynamic STE.
- Dynamic STE involved 1 ST-segment change in 11.1% and ≥2 changes in 4.5% of patients.
- STEMI was identified on a subsequent ECG in 8.0% of cases initially showing no STEMI.
Conclusions:
- Prehospital serial 12-lead ECGs identified STEMI in 8% of patients with an initial non-STEMI ECG by recognizing transient ST-segment changes during transport.
- This method demonstrates value in improving STEMI detection within emergency medical services.
Objective:
Repeated or serial 12-lead electrocardiograms (ECGs) in the prehospital setting may improve management of patients with subtle ST-segment elevation (STE) or with a ST-segment elevation myocardial infarction (STEMI) that evolves over time. However, there is a minimal amount of scientific evidence available to support the clinical utility of this method. Our objective was to evaluate the use of serial 12-lead ECGs to detect STEMI in patients during transport in a Canadian emergency medical services (EMS) jurisdiction.
Methods:
We performed a retrospective study of suspected STEMI patients transported by EMS in the Chaudière-Appalaches region (Québec, Canada) between August 2006 and December 2013. Patients were monitored by a serial 12-lead ECG system where an averaged ECG was transmitted every 2 minutes. Following review by an emergency physician, ECGs were grouped as having either a persistent STE or a dynamic STE that evolved over time.
Results:
A total of 754 suspected STEMI patients were transported by EMS during the study period. Of these, 728 patients met eligibility criteria and were included in the analysis. A persistent STE was observed in 84.3% (614/728) of patients, while the remaining 15.7% (114/728) had a dynamic STE. Among those with dynamic STE, 11.1% (81/728) had 1 ST-segment change (41 no-STEMI to STEMI; 40 STEMI to no-STEMI) and 4.5% (33/728) had ≥ 2 ST-segment changes (17 no-STEMI to STEMI; 16 STEMI to no-STEMI). Overall, in 8.0% (58/728) of the cohort, STEMI was identified on a subsequent ECG following an initial no-STEMI ECG.
Conclusions:
Through recognition of transient ST-segment changes during transport via the prehospital serial 12-lead ECG system, STEMI was identified in 8% of suspected STEMI patients who had an initial no-STEMI ECG. Key words: electrocardiography; emergency medical services; ST-elevation myocardial infarction; prehospital dynamic ECG.
Related Concept Videos
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
Serial Position Effect
Phase-lead and Phase-lag Controllers
Time and frequency -Domain Interpretation of Phase-lead Control
The design of phase-lead control involves the strategic placement of poles and zeros to balance steady-state error and system...
Detection of Gross Error: The Q Test

