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[Addictions].

Jacques Besson1, Jeremy Grivel1, Alexander Tomei1

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This summary is machine-generated.

This review covers addiction research, criticizing the disease model by highlighting personal agency. It also updates on cannabidiol, legal cannabis, gambling suicidality prevention, and integrated care for addiction and psychosis.

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Area of Science:

  • Neuroscience
  • Clinical Pharmacology
  • Psychiatry

Background:

  • Current addiction models are challenged by cognitive neurosciences emphasizing personal agency.
  • Societal relevance includes updates on cannabidiol and legal cannabis.
  • Specific populations like excessive gamblers and individuals with first psychotic episodes require tailored interventions.

Purpose of the Study:

  • To critically evaluate the disease model of addiction.
  • To provide an update on the clinical pharmacology of cannabidiol and legal cannabis.
  • To discuss specific prevention strategies for gambling-related suicidality and integrated care for addiction with first psychotic episodes.

Main Methods:

  • Literature review and critical analysis of current addiction research.
  • Pharmacological review of cannabidiol and its relation to legal cannabis.
  • Analysis of epidemiological data and clinical guidelines for specific addiction-related issues.

Main Results:

  • Cognitive neurosciences challenge the traditional disease model of addiction, advocating for agentivity.
  • Cannabidiol's clinical pharmacology and the landscape of legal cannabis are updated.
  • Evidence suggests specific prevention strategies for excessive gambler suicidality and the need for integrated care for co-occurring addiction and psychosis.

Conclusions:

  • Addiction research requires a nuanced approach, integrating neuroscientific findings on agentivity.
  • Understanding the pharmacology of substances like cannabidiol is crucial in the context of evolving cannabis regulations.
  • Integrated care models are essential for addressing complex conditions such as gambling disorder with suicidality and comorbid addiction with first psychotic episodes.