Related Experiment Video
Updated: Feb 15, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
[Antiretroviral treatments : towards simplified regimens ?]
Olivier Nawej Tshikung1, Alexandra Calmy1
1Unité VIH/sida, Service des maladies infectieuses, HUG, 1211 Genéve 14.
Abstract:
The chronicity of HIV infection and the use of antiretroviral therapy among all individuals living with HIV necessitate new treatment strategies. Alternatives to lifelong tri-therapy treatment are under investigation with the aim to improve the quality of life of patients. New therapies with longer half-lives or « biological » treatments are also under study in clinical trials in order to develop streamlined maintenance strategies. These simplified therapies represent the near future of HIV management both with regards to less toxic molecules and a change in the traditional dogma of tri-therapy, including the daily dose thanks to the possibility of dosage only on certain weekdays or via molecules under development with a long duration of action.
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