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Updated: Feb 15, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Susceptibility Weighted MRI in Rodents at 9.4 T
Ferdinand Schweser1,2, Marilena Preda3,4, Robert Zivadinov3,4
1Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, USA. schweser@buffalo.edu.
None:
Susceptibility Weighted Imaging (SWI) is an established part of the clinical neuroimaging toolbox and, since its inception, has also successfully been used in various preclinical studies. Exploiting the effect of variations of magnetic susceptibility between different tissues on the externally applied, static, homogeneous magnetic field, the method visualizes venous vasculature, hemorrhages and blood degradation products, calcifications, and tissue iron deposits. The chapter describes in vivo and ex vivo protocols for preclinical SWI in rodents.
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