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Area of Science:

  • Neurology
  • Ophthalmology
  • Vestibular Disorders

Background:

  • Visual vertigo presents with dizziness and disorientation triggered by visual stimuli.
  • Current treatments like vestibular rehabilitation therapy are insufficient for resistant cases, highlighting the need for pharmacotherapy.

Purpose of the Study:

  • To assess the effectiveness of oral acetazolamide in alleviating visual vertigo symptoms.
  • To investigate the association between acetazolamide and symptom improvement in a patient cohort.

Main Methods:

  • A comparative case series included adult patients diagnosed with visual vertigo, excluding those with organic causes.
  • Patients were categorized into three groups: current acetazolamide users, past users, and non-users.
  • Symptom improvement was evaluated via a voluntary phone survey, focusing on subjective percentage improvement and trigger-specific relief.

Main Results:

  • Overall symptomatic improvement was reported by 94.7% of current acetazolamide users, 66.7% of past users, and 45.5% of non-users.
  • The difference in improvement across groups was statistically significant (p = 0.0061).
  • The greatest symptom relief was observed for visual vertigo triggered by being a passenger in a car.

Conclusions:

  • Acetazolamide demonstrates a positive association with symptom improvement in patients suffering from visual vertigo.
  • These findings suggest acetazolamide as a potential therapeutic option for visual vertigo, particularly for treatment-resistant cases.