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Updated: Feb 15, 2026

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
Published on: May 25, 2011
Transient chaos and associated system-intrinsic switching of spacetime patterns in two synaptically coupled layers of
Harrison Hartle1, Renate Wackerbauer1
1Department of Physics, University of Alaska, Fairbanks, Alaska 99775-5920, USA.
Abstract:
Spatiotemporal chaos collapses to either a rest state or a propagating pulse solution in a single layer of diffusively coupled, excitable Morris-Lecar neurons. Weak synaptic coupling of two such layers reveals system intrinsic switching of spatiotemporal activity patterns within and between the layers at irregular times. Within a layer, switching sequences include spatiotemporal chaos, erratic and regular pulse propagation, spontaneous network wide neuron activity, and rest state. A momentary substantial reduction in neuron activity in one layer can reinitiate transient spatiotemporal chaos in the other layer, which can induce a swap of spatiotemporal chaos with a pulse state between the layers. Presynaptic input maximizes the distance between propagating pulses, in contrast to pulse merging in the absence of synapses.
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