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Updated: Feb 15, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Theory of microphase separation in bidisperse chiral membranes
Raunak Sakhardande1, Stefan Stanojeviea1, Arvind Baskaran1
1Martin Fisher School of Physics, Brandeis University, Waltham, Massachusetts 02453, USA.
Abstract:
We present a Ginzburg-Landau theory of microphase separation in a bidisperse chiral membrane consisting of rods of opposite handedness. This model system undergoes a phase transition from an equilibrium state where the two components are completely phase separated to a state composed of microdomains of a finite size comparable to the twist penetration depth. Characterizing the phenomenology using linear stability analysis and numerical studies, we trace the origin of the discontinuous change in microdomain size that occurs during this phase transition to a competition between the cost of creating an interface and the gain in twist energy for small microdomains in which the twist penetrates deep into the center of the domain.
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