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Updated: Feb 15, 2026

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
Published on: June 13, 2025
Sleep disruption in caregivers of pediatric stem cell recipients
Kristen Coleman1,2, Laura Flesch1,2, Lisa Petiniot1
1Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Insights
Hospitalized children undergoing hematopoietic stem cell transplant (HSCT) disrupt caregiver sleep. Most caregivers reported poor sleep quality and insufficient sleep duration, highlighting the need for interventions.
Area of Science:
- Pediatric Hematology
- Sleep Medicine
- Caregiver Support
Background:
- Parental/caregiver sleep disruption is a significant concern during pediatric hospitalization.
- Hospital environments can exacerbate sleep disturbances for caregivers of critically ill children.
Purpose of the Study:
- To quantitatively and qualitatively evaluate sleep patterns in parents/caregivers of children undergoing hematopoietic stem cell transplant (HSCT).
- To assess the frequency of nighttime room entries for patients undergoing HSCT.
Main Methods:
- Cross-sectional study involving 17 parents/caregivers and 189 patient nights.
- Quantitative sleep assessment and qualitative interviews with caregivers.
- Objective recording of patient room entries.
Main Results:
- 71% of caregivers experienced significant sleep disturbance and reported poor sleep quality.
- 88% of caregivers slept less than 6 hours per night, with 82% awakening at least four times nightly.
- Patient rooms were entered a median of 12 times per night.
Conclusions:
- Caregivers of children undergoing HSCT experience substantial sleep disruption.
- Frequent nighttime awakenings and environmental disturbances contribute to poor sleep.
- Further research and interventions are needed to improve caregiver sleep during pediatric HSCT hospitalization.
Abstract:
Parents/caregivers of hospitalized patients are at risk of sleep disruption. We performed a cross-sectional quantitative and qualitative evaluation of sleep in parents/caregivers of children undergoing hematopoietic stem cell transplant (HSCT; n = 17). Additionally, we explored the frequency of room entries for hospitalized patients undergoing HSCT (n = 189 nights). Twelve caregivers (71%) demonstrated significant sleep disturbance, 12 (71%) described sleep quality as poor, 15 (88%) averaged < 6 hours of sleep per night, 14 (82%) awakened at least four times per night. Patient rooms were entered a median of 12 times per night (interquartile range 10-15). Intervention studies to improve caregiver sleep during hospitalization are needed.
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