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Published on: January 13, 2026
Venous Ports in Infants
Michael Acord1, Anne Marie Cahill1, Ganesh Krishnamurthy1
1Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA 19014.
Insights
Pediatric venous port placement is technically successful. Left-sided ports increase infection risk, while lower infant weight elevates mechanical complication risk.
Area of Science:
- Pediatric Surgery
- Vascular Access Devices
- Infectious Disease Prevention
Background:
- Venous port placement is crucial for long-term intravenous access in infants.
- Complications such as infections and mechanical issues can arise, impacting patient outcomes.
- Identifying risk factors is essential for optimizing safety in this vulnerable population.
Purpose of the Study:
- To assess the technical success rate of venous port placement in infants.
- To determine the incidence of mechanical and infectious complications.
- To identify risk factors associated with these complications.
Main Methods:
- Retrospective cohort study of 64 infants (<1 year) undergoing venous port placement.
- Data collected included patient demographics, placement details, and complication events.
- Analysis focused on technical success, central catheter-associated bloodstream infections (CCABSIs), and mechanical complications.
Main Results:
- 100% technical success rate for venous port placement.
- 13 central catheter-associated bloodstream infections (CCABSIs) occurred (0.63 per 1,000 catheter-days), with 8 requiring removal.
- Increased risk of CCABSIs with left-sided port placement (RR 3.22) and mechanical complications in the lowest weight quartile (RR 4.37).
Conclusions:
- Venous port placement in infants achieves high technical success.
- Left-sided placement is a risk factor for infectious complications (CCABSIs).
- Lower infant weight is associated with an increased risk of mechanical complications.
Purpose:
To evaluate technical success and the incidences of, and risk factors for, mechanical and infectious complications of venous port placement in infants.
Materials And Methods:
This was a retrospective single-institution cohort study of port placement in infants (age < 1 y) from January 2006 through June 2016 (mean age, 7.5 mo ± 3.3; mean weight, 8.1 kg ± 1.9). Age, weight, sex, side of placement, tip position, and indication for placement (chemotherapy vs other) were recorded. Total catheter-days (CDs), mechanical complications, and central catheter-associated bloodstream infections (CCABSIs) were identified.
Results:
During the study years, 64 ports were placed in 64 infants, with a technical success rate of 100%. The mean catheter life was 321 days (total range, 4-1,917 d; interquartile range [IQR], 107-421 d). There were 13 CCABSI events (0.63 per 1,000 CDs); of these, 8 (12.5% among 64 patients) required port removal for infection. There was an increase in CCABSIs in patients with left-sided port placement (relative risk [RR], 3.22; 95% confidence interval [CI], 1.02-10.14; P = .05). There were 8 mechanical complications of the port reservoir or catheter (0.39 per 1,000 CDs). Of these, 2 (3.1%) required removal. Patients in the lowest weight quartile were at an increased risk of mechanical complications (RR, 4.37; 95% CI, 1.09-17.48; P = .04).
Conclusions:
Venous ports can be placed with a high rate of technical success in infants. Left-sided ports and low weight are associated with increased infectious and mechanical complications, respectively.
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