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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

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Anterior Segment Imaging for Angle Closure.

Sunee Chansangpetch¹, Prin Rojanapongpun², Shan C Lin³

¹Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Department of Ophthalmology, University of California, San Francisco Medical School, San Francisco, California.

American Journal of Ophthalmology

|January 22, 2018

Summary

This summary is machine-generated.

Anterior segment imaging (AS-imaging) offers advantages over gonioscopy for diagnosing and managing angle closure. This technology provides better documentation and risk assessment, potentially becoming a future standard of care.

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Area of Science:

Ophthalmology
Medical Imaging
Glaucoma Research

Background:

Gonioscopy is the current standard for assessing the anterior chamber angle.
Gonioscopy has limitations in reproducibility and documentation.
Understanding anterior segment anatomy is crucial for diagnosing angle closure glaucoma.

Purpose of the Study:

To review the role of anterior segment imaging (AS-imaging) in angle closure diagnosis and management.
To compare AS-imaging with gonioscopy.
To highlight the advantages of AS-imaging over gonioscopy.

Main Methods:

Literature review and expert perspective.
Focused on anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM).
Interpreted publications on AS-imaging for angle closure assessment.

Main Results:

AS-imaging demonstrates comparable or superior performance to gonioscopy in angle closure detection.
AS-imaging offers enhanced reproducibility and documentation for long-term follow-up.
Qualitative and quantitative data from AS-imaging improve understanding of angle closure mechanisms and aid risk stratification.

Conclusions:

AS-imaging is increasingly valuable for angle closure screening and management.
AS-imaging should be integrated as an adjunctive tool in clinical practice.
AS-imaging may be considered for first-line screening in high-risk patients.