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Updated: Feb 15, 2026

Transcranial Direct Current Stimulation tDCS in Mice
Published on: September 23, 2018
Facilitation of Function and Manipulation Knowledge of Tools Using Transcranial Direct Current Stimulation (tDCS)
Ryo Ishibashi1,2, Tatsuya Mima3, Hidenao Fukuyama4,5
1Neuroscience and Aphasia Research Unit, Division of Neuroscience and Experimental Psychology, University of Manchester, Manchester, United Kingdom.
This study used transcranial direct current stimulation (tDCS) to enhance tool cognition in individuals with brain damage. Anodal tDCS over the anterior temporal lobe and inferior parietal lobule improved recognition and manipulation of tools.
Area of Science:
- Neuroscience
- Cognitive Science
- Neurology
Background:
- Tool use is fundamental to human life.
- Brain damage and neurological disorders often impair tool cognition.
- The anterior temporal lobe (ATL) and inferior parietal lobule (IPL) are key brain regions for action semantics.
Purpose of the Study:
- To investigate the efficacy of transcranial direct current stimulation (tDCS) in improving tool-related cognition.
- To identify the specific roles of the ATL and IPL in tool semantics.
Main Methods:
- Anodal tDCS was applied over the ATL and IPL.
- Participants completed two cognitive tasks assessing tool function and manipulation knowledge.
- Performance was compared between stimulation conditions.
Main Results:
- Anodal tDCS over ATL and IPL significantly enhanced performance in tool cognition tasks.
- ATL stimulation improved access to both tool function and manipulation knowledge.
- IPL stimulation showed a trend towards improved manipulation judgments.
Conclusions:
- tDCS over ATL and IPL offers a novel approach to enhance tool cognition.
- Findings support the role of ATL and IPL in supporting action semantics.
- This method could aid in rehabilitation for patients with cognitive deficits.
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