Related Experiment Video
Updated: Feb 15, 2026

Comparative Lesions Analysis Through a Targeted Sequencing Approach
Published on: November 5, 2019
Lesions Without Borders: Scrotal Lesions That Involve Both the Intratesticular and Extratesticular Regions
Massihullah Hamidi1, Paul Nikolaidis1, Frank H Miller1
11 Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Ste 800, Chicago, IL 60611.
Objective:
Differentiation of scrotal lesions is often dictated by whether they are intraor extratesticular. However, these regions are not entirely isolated, and disease processes can span both spaces. We review a variety of lesions that can involve both regions, describe the relevant anatomy, and illustrate their imaging appearances.
Conclusion:
Identification of involvement of both intra- and extratesticular regions by a single process can narrow the differential considerations and help arrive at the correct diagnosis.
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