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Multinucleate cell angiohistiocytoma.

Austin H Nguyen1, David J Glembocki2, Neel B Patel2

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Multinucleate cell angiohistiocytoma (MCAH) is a rare skin condition presenting as grouped papules. This case report details MCAH in an elderly male, reviewing its pathogenesis and treatment options.

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Multinucleate cell angiohistiocytoma (MCAH) is an uncommon benign vascular proliferation of the skin.
  • It typically presents as erythematous to violaceous papules, often in clusters.

Observation:

  • A case of MCAH is presented in an 83-year-old Caucasian male.
  • The lesions were located on the right anterior thigh and left posterior calf.

Findings:

  • Histopathologic examination revealed characteristic vascular proliferations.
  • Multinucleate giant cells and dermal fibrosis were key findings upon microscopic analysis.

Implications:

  • This report contributes to the understanding of MCAH presentation and histology.
  • Reviewing pathogenesis and therapeutic modalities aids in clinical management of this rare entity.