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Updated: Feb 15, 2026

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
Published on: January 12, 2018
Rectal red blood loss in a healthy toddler is not always a juvenile polyp
Insights
Heterotopic gastric mucosa in the rectum is rare but should be considered in children with rectal bleeding. Early diagnosis and biopsy during endoscopy are crucial for effective treatment.
Area of Science:
- Gastroenterology
- Pediatric Surgery
- Pathology
Background:
- Heterotopic gastric mucosa is a congenital anomaly typically found in Meckel's diverticula and duplication cysts.
- Solitary heterotopic gastric mucosa in the rectum is a rare condition often overlooked.
Observation:
- A 3-year-old girl presented with recurrent rectal bleeding due to solitary rectal heterotopic gastric mucosa.
- Symptoms in children include rectal bleeding (96%), pain (46%), and perineal ulcers (25%).
- Endoscopic findings vary, including mucosal elevations, polyps, and solitary ulcers.
Findings:
- This case adds to the 34 adults and 24 children previously reported with rectal heterotopic gastric mucosa.
- A male predominance (69%) is observed in reported cases.
- Children typically present with bleeding, while adults more frequently have polyps.
Implications:
- Rectal heterotopic gastric mucosa should be included in the differential diagnosis for children with recurrent rectal bleeding.
- Endoscopic biopsy is essential for diagnosis.
- Treatment approaches differ between children (primarily surgical) and adults (more endoscopic techniques).
Abstract:
Aim Heterotopic gastric mucosa is a well-known congenital anomaly in Meckel's diverticula and duplication cysts. Solitary heterotopic gastric mucosa in the rectum is a rare and frequently overlooked abnormality. Starting from a patient history, the literature is searched and all cases reported over the past 20 years are reviewed and compared to a summary of the older cases. Differences between adult and childhood presentation are outlined and our patient is compared with prior reported cases. Case A 3-year-old girl presented with recurrent rectal blood loss caused by heterotopic gastric mucosa without duplication cyst. She was endoscopically treated with two-stage endoscopic surgical dissection (ESD). Up to now, rectal heterotopic gastric mucosa has been reported in 34 adults and 24 children, including this patient. There is an overall male dominance (69%). Presenting complaints in children were recurrent fresh blood loss per anum (96%), pain (46%), perineal ulcers (25%), diarrhoea (8%) and one patient had an ano-cutaneous fistula. Endoscopy revealed a mucosal elevation with a slightly different aspect (33%), a polyp (42%) and a solitary ulcer (25%). Endoscopy in adults reveals more frequently polyps compared to children. Treatment in childhood is mainly surgical where adults are more frequently treated with endoscopic techniques. Conclusion In a child with recurrent rectal bleeding in good general health, it is important to withhold heterotopic gastric mucosa in the differential diagnosis and take sufficient biopsies during endoscopy.
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