Related Experiment Video
Updated: Feb 15, 2026

Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells
Published on: February 18, 2016
The rise of three-dimensional human brain cultures
11Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
Abstract:
Pluripotent stem cells show a remarkable ability to self-organize and differentiate in vitro in three-dimensional aggregates, known as organoids or organ spheroids, and to recapitulate aspects of human brain development and function. Region-specific 3D brain cultures can be derived from any individual and assembled to model complex cell-cell interactions and to generate circuits in human brain assembloids. Here I discuss how this approach can be used to understand unique features of the human brain and to gain insights into neuropsychiatric disorders. In addition, I consider the challenges faced by researchers in further improving and developing methods to probe and manipulate patient-derived 3D brain cultures.
Related Concept Videos
Rise of Liquid in a Capillary Tube
Dimensional Analysis
Conversion Factors and Dimensional Analysis
The unit...
Dimensional Analysis
In fluid mechanics, dimensional...
Dimensional Analysis
Dimensional analysis allows us to analyze and compare physical quantities on a...
Dimensional Analysis
Three-Dimensional Force System

