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Timing matters: Genetic regulation of neuronal maturation in the primate brain
Kent Imaizumi1, Sergiu P Paşca1
1Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Stanford Brain Organogenesis Program, Wu Tsai Neurosciences Institute & Bio-X, Stanford, CA 94305, USA.
Abstract:
The molecular mechanisms that govern the extended neuronal maturation in the primate brain remain incompletely understood. In this issue of Neuron, Gao et al.1 measure gene activity, chromatin state, and electrical properties of individual neurons in the macaque to reveal some of the genetic regulators of neuronal maturation in the cerebral cortex.
