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Updated: Feb 15, 2026

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
Published on: October 13, 2011
Force depression following a stretch-shortening cycle is independent of stretch peak force and work performed during
Rafael Fortuna1, Hannah Kirchhuebel2, Wolfgang Seiberl2
1Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada. fortuna.rafael@gmail.com.
Abstract:
The steady-state isometric force following active muscle shortening or lengthening is smaller (force depression; FD) or greater (residual force enhancement; RFE) than a purely isometric contraction at the corresponding length. The mechanisms behind these phenomena remain not fully understood, with few studies investigating the effects of FD and RFE in stretch-shortening cycles (SSC). The purpose of this study was to investigate the influence of RFE and peak force at the end of the stretch phase on the steady-state isometric force following shortening. Isometric thumb adduction force measurements were preceded by an isometric, a shortening contraction to induce FD, and SSCs at different stretch speeds (15°/s, 60°/s, and 120°/s). The different peak force values at the end of stretch and the different amounts of work performed during shortening did not influence the steady-state isometric force at the end of the SSC. We conclude that the FD following SSC depends exclusively on the amount of RFE established in the initial stretch phase in situations where the timing and contractile conditions of the shortening phase are kept constant .
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