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Role of immunotherapy in bladder cancer: past, present and future

Sabeeh-Ur-Rehman Butt1, Laeeq Malik2,3

  • 1Department of Medical Oncology, The Canberra Hospital, Garran, ACT, 2605, Australia. sabeeh.butt@act.gov.au.

Cancer Chemotherapy and Pharmacology
|January 26, 2018
PubMed

Insights

Bladder cancer treatment is advancing with immunotherapy, including new drugs targeting immune responses. Research is exploring novel immunotherapeutic agents to improve patient outcomes.

Area of Science:

  • Oncology
  • Immunotherapy
  • Urologic Oncology

Background:

  • Oncology research is shifting towards immunomodulation for cancer treatment.
  • Bladder cancer treatment has seen significant advancements with immunotherapy.

Purpose of the Study:

  • To review the role of immunotherapy in bladder cancer treatment.
  • To discuss emerging immunotherapeutic agents for bladder cancer.

Main Methods:

  • Literature review of recent advancements in bladder cancer immunotherapy.
  • Analysis of approved immunotherapeutic agents and ongoing research.

Main Results:

  • Five immunotherapeutic agents have been approved for metastatic bladder cancer.
  • Anti-programmed cell death-1 (anti-PD-1) and anti-programmed cell death ligand-1 (anti-PDL-1) therapies have shown initial success.

Conclusions:

  • The field of bladder cancer immunotherapy is rapidly evolving.
  • Identification and validation of new immune targets are crucial for future treatments.
Keywords:
Bladder cancerImmunotherapy

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