Clinical Profile of Scleritis in Children

Parthopratim Dutta Majumder1, Sowkath Ali1, Amala George1

  • 1a Department of Uvea , Sankara Nethralaya , Chennai , India.

Insights

This study reveals that scleritis in children, particularly posterior scleritis, presents differently than in adults. Tuberculosis was the primary systemic association found in pediatric cases.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Rheumatology

Background:

  • Scleritis is a rare but serious inflammatory eye condition.
  • Understanding its clinical patterns in children is crucial for timely diagnosis and management.

Purpose of the Study:

  • To characterize the clinical presentation of scleritis in pediatric patients (≤16 years).
  • To identify common subtypes and systemic associations of childhood scleritis.

Main Methods:

  • Retrospective analysis of medical records from 20 children (24 eyes) with scleritis.
  • Data collected included demographics, visual acuity, scleritis subtype, laboratory results, and treatment.

Main Results:

  • Mean age at presentation was 12.2 years; 80% of cases were unilateral.
  • Posterior scleritis (41.7%) was most common, followed by nodular anterior scleritis (33.3%).
  • Tuberculosis was the sole systemic association, identified in 15% of patients.

Conclusions:

  • Pediatric scleritis exhibits distinct clinical features compared to adult populations.
  • Early recognition of scleritis subtypes and associated conditions like tuberculosis is vital in children.

Related Concept Videos

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.2K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
335
Nursing Clinical Information System01:27

Nursing Clinical Information System

Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.3K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.9K
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.1K
Taping Over Different Ground Profiles01:12

Taping Over Different Ground Profiles

Taping over varying ground profiles requires careful adaptation to achieve accurate measurements. On smooth, level ground with minimal vegetation, the tape can rest directly on the ground. Here, the taping team, typically consisting of a head and a rear tapeman, coordinates their positions with clear communication. The rear tapeman holds the tape at the starting point and guides the head tapeman toward a range pole placed beyond the endpoint, using hand or voice signals to ensure alignment.On...
411