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Soft Tissue Rosai-Dorfman Disease: Case report
Rubyath C Rajib1, Rajasekharan Pillai1, Ibrahim A Sulaiman1
1Department of Pathology & Laboratory Medicine, Sultan Qaboos Hospital, Salalah, Oman.
Sultan Qaboos University Medical Journal
|January 27, 2018
Summary
Rosai-Dorfman disease (RDD) is a rare histiocytic disorder. This case highlights isolated soft tissue RDD (STRDD) in a young male, emphasizing surgical excision as the primary treatment.
Area of Science:
- Histopathology
- Oncology
- Dermatology
Background:
- Rosai-Dorfman disease (RDD) is a rare histiocytic proliferative disorder typically presenting with massive lymphadenopathy.
- Extranodal involvement is known in generalized RDD, but isolated soft tissue RDD (STRDD) is exceptionally uncommon.
Observation:
- A 17-year-old male presented with a painless, slow-growing cheek mass.
- Diagnostic workup included routine histopathology and immunohistochemistry.
Findings:
- The patient was diagnosed with isolated soft tissue Rosai-Dorfman disease (STRDD).
- Histopathological and immunohistochemical examinations confirmed the diagnosis.
Implications:
- Surgical excision is currently the most effective treatment for STRDD.
- STRDD should be considered in the differential diagnosis of soft tissue histiocytic lesions due to its rarity.
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