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Related Concept Videos

Cancer02:18

Cancer

54.6K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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What is Cancer?02:12

What is Cancer?

14.5K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Cancer Therapies02:49

Cancer Therapies

10.2K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.2K
Cancer Vaccines01:30

Cancer Vaccines

1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Skin Cancer01:30

Skin Cancer

6.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Updated: Feb 15, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

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The microbiome and cancer.

Brian Goodman1, Humphrey Gardner1

  • 1Evelo Biosciences, Cambridge, MA, USA.

The Journal of Pathology
|January 30, 2018
PubMed
Summary
This summary is machine-generated.

The human microbiome, including bacteria, fungi, and viruses, plays a role in cancer development. Advanced sequencing reveals molecular links between the gut microbiome and cancer, mediated by direct and immune responses.

Keywords:
evolution of cancermetabolomics of cancermicrobiomenext-generation sequencing

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Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
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Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
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Area of Science:

  • Microbiology
  • Oncology
  • Immunology

Background:

  • Humans host a complex microbiome (bacteria, fungi, viruses) with long-standing evolutionary ties.
  • Epidemiological links between bacteria and cancer are increasingly understood at the molecular level.
  • Next-generation sequencing enables detailed exploration of the human gut microbiome.

Purpose of the Study:

  • To explore the relationship between the microbiome and cancer.
  • To elucidate molecular mechanisms linking microbes to cancer development.

Main Methods:

  • Utilizing next-generation sequencing to analyze microbiome composition (taxonomic and metabolomic).
  • Investigating direct and immunological mechanisms of microbial influence on tumors.
  • Analyzing host-microbe interactions in various body niches.

Main Results:

  • Established taxonomic and metabolomic relationships between the gut microbiome and cancer.
  • Identified causal mechanisms involving microbes within tumors.
  • Demonstrated microbial influence on cancer through immunological pathways.

Conclusions:

  • The human microbiome is intricately linked to cancer.
  • Microbial factors can directly and indirectly (immunologically) contribute to cancer.
  • Further research into microbiome-cancer interactions is warranted.