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Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

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The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
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Nuclear Magnetic Resonance (NMR): Overview01:07

Nuclear Magnetic Resonance (NMR): Overview

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Nuclear magnetic resonance (NMR) is a phenomenon exhibited by certain nuclei that can absorb characteristic radio frequency radiation under certain conditions. NMR has been extensively applied in molecular spectroscopy and medical diagnostic imaging. In both these applications, the molecule or subject under study is placed in a magnetic field and irradiated with radio frequency energy.
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
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Resonance02:52

Resonance

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The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
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Colors and Magnetism03:02

Colors and Magnetism

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Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
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Related Experiment Video

Updated: Feb 15, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

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Cryogenic Preamplifiers for Magnetic Resonance Imaging.

Daniel H Johansen, Juan D Sanchez-Heredia, Jan R Petersen

    IEEE Transactions on Biomedical Circuits and Systems
    |January 30, 2018
    PubMed
    Summary
    This summary is machine-generated.

    Cryogenic preamplifiers improve magnetic resonance imaging (MRI) sensitivity by reducing electronic noise. This study demonstrates an 8% signal-to-noise ratio increase in MRI using a 77 K preamplifier.

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    Area of Science:

    • Medical Imaging
    • Electronics Engineering
    • Cryogenics

    Background:

    • Achieving ultimate detection limits in Magnetic Resonance Imaging (MRI) necessitates reducing electronic circuit thermal noise.
    • Emerging cryogenic coils for MRI require complementary cryogenic preamplifiers to maximize their potential.

    Purpose of the Study:

    • To design and implement a cryogenic preamplifier for MRI applications.
    • To evaluate the performance of a preamplifier operated at cryogenic temperatures (77 K).

    Main Methods:

    • A cryogenic preamplifier was designed using a high electron mobility transistor (ATF54143) in a common source configuration.
    • Auxiliary circuitry including a noise-free voltage regulator, switch, and active detuning trigger was implemented.
    • The preamplifier was tested at 77 K for Carbon (C) imaging at 3 Tesla (32.13 MHz).

    Main Results:

    • The cryogenic preamplifier achieved a gain of 18 dB and a noise temperature of 13.7 K.
    • Imaging experiments showed an 8% increase in signal-to-noise ratio (from 365 to 399) when the preamplifier temperature was reduced from 296 K to 77 K.
    • This improvement was observed while the MRI coil remained at room temperature.

    Conclusions:

    • The developed cryogenic preamplifier effectively reduces noise and enhances MRI signal-to-noise ratio.
    • This work facilitates the integration of cryogenic coils and preamplifiers for improved MRI detection limits.
    • The findings pave the way for advancing the ultimate sensitivity in MRI technology.