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How to conduct implementation trials and multicentre studies in the emergency department
Ian G Stiell1, Jeffrey J Perry1, Jamie Brehaut2
1*Department of Emergency Medicine,University of Ottawa,Ottawa,ON.
CJEM
|January 31, 2018
Summary
This study offers eight recommendations to improve the design and conduct of multicenter studies and implementation research in emergency medicine. These findings aim to overcome barriers and facilitate future clinical research in emergency departments.
Area of Science:
- Emergency Medicine
- Clinical Research Methodology
- Implementation Science
Background:
- Conducting multicenter studies and implementation trials in emergency medicine presents unique challenges.
- Understanding barriers and facilitators is crucial for advancing research in this field.
Purpose of the Study:
- To provide an overview and recommendations for conducting implementation trials and multicenter studies in emergency medicine.
- To identify barriers and facilitators to these study types through researcher interviews.
Main Methods:
- Convened a panel of methodologists to discuss study design and conduct.
- Conducted semi-structured interviews with 37 Canadian emergency medicine researchers.
- Thematic analysis of interview responses to develop recommendations.
Main Results:
- Eight key recommendations were developed to facilitate multicenter clinical and implementation studies.
- Identified critical factors including local investigator support, research infrastructure, and inter-site communication.
Conclusions:
- Guidance is provided for conducting implementation research specifically within emergency departments.
- Recommendations emphasize the importance of collaboration and dedicated resources for successful multicenter research.
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