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Relationship between CNS and Immunology: Correlation with Psychology
Ghulam Md Ashraf1, Asim Azhar2, Qamar Zia2,3
1King Fahd Medical Research Center, King Abdulaziz University, Saudi Arabia.
Current Drug Metabolism
|January 31, 2018
Summary
The bidirectional network between the central nervous system (CNS) and immune system is crucial for health. Dysregulation, especially in aging, contributes to neurodegenerative diseases and psychiatric disorders.
Area of Science:
- Neuroscience
- Immunology
- Psychology
Background:
- The human central nervous system (CNS) and immune system protect against disease.
- Inflammatory and neural pathway alterations cause global health concerns.
- Bidirectional network deregulation, particularly in aging, leads to neurodegenerative diseases like dementia.
Purpose of the Study:
- To explore the link between the immune system and CNS diseases.
- To understand the biological mechanisms of psychoneuroimmunological disorders.
- To highlight the connection between psychology, emotion, disease, and immunology.
Main Methods:
- Literature review and synopsis of existing research.
- Analysis of the interplay between CNS and immune system functions.
- Examination of immune response in psychiatric disorders.
Main Results:
- Immune system plays a vital role in protecting against pathogens.
- Altered immune regulation is implicated in various brain diseases.
- Psychoneuroimmunological disorders arise from complex CNS-immune interactions.
Conclusions:
- A strong relationship exists between emotion, psychology, disease, and immunology.
- Mechanistic understanding of psychoneuroimmunological disorders requires further attention.
- The CNS and immune system are intricately linked in health and disease.
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