Good at One or Good at All? Variability of Coronary and Valve Operation Outcomes Within Centers

Lily E Johnston1, Emily A Downs1, Robert Hawkins1

  • 1Department of Surgery, Division of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Virginia.

Insights

Center performance in coronary artery bypass grafting (CABG) and heart valve surgery outcomes do not correlate for mortality. However, morbidity rates show a strong correlation, suggesting postoperative care impacts both procedures.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Health Services Research

Background:

  • Technical expertise for coronary artery bypass grafting (CABG) and structural heart valve disease treatment differs.
  • A correlation between center-specific mortality rates for CABG and valve operations has not been established.
  • This study investigated whether risk-adjusted outcomes for coronary and valve procedures correlate within institutions.

Purpose of the Study:

  • To test the hypothesis that risk-adjusted outcomes between coronary artery bypass grafting (CABG) and heart valve operations do not correlate within medical centers.
  • To analyze the relationship between institutional performance in CABG and valve procedures.
  • To identify potential determinants of patient outcomes in cardiac surgery.

Main Methods:

  • Utilized a multi-institutional Society of Thoracic Surgeons (STS) database (2008-2015) including isolated CABG, aortic valve replacement (AVR), and mitral valve replacement (MVR) procedures.
  • Calculated observed-to-expected (O/E) ratios for morbidity and mortality based on STS predicted risks for each institution and procedure.
  • Employed linear regression models to assess the relationship between institutional performance in CABG and valve operations.

Main Results:

  • Analyzed 22,258 procedures (17,026 CABG, 3,238 AVR, 1,994 MVR) across 18 institutions.
  • Weak correlation coefficients were observed for mortality: 0.22 (AVR vs. CABG) and 0.26 (MVR vs. CABG).
  • A strong relationship was found for morbidity O/E ratios: 1.03 (AVR) and 0.97 (MVR), indicating a nearly 1:1 correlation between institutional morbidity for CABG and valve operations.

Conclusions:

  • Institutions with low CABG mortality rates may not exhibit similarly low valve operation mortality rates.
  • A striking, nearly identical O/E ratio for morbidity was observed for CABG and valve operations at each center.
  • These findings suggest that postoperative care is a significant determinant of morbidity following cardiac operations.
Abstract

Related Concept Videos

Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
12.6K
Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
12.5K
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Center of Gravity00:58

Center of Gravity

The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
6.8K
Center of Gravity01:15

Center of Gravity

The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
2.2K
Variability: Analysis01:11

Variability: Analysis

Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
541