Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocrine Signaling01:45

Endocrine Signaling

68.3K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
68.3K
What is the Endocrine System?00:46

What is the Endocrine System?

421.9K
The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
421.9K
The Endocrine System01:29

The Endocrine System

1.4K
The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
1.4K
An Overview of the Endocrine System01:10

An Overview of the Endocrine System

14.4K
The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
14.4K
Structures of the Endocrine System00:59

Structures of the Endocrine System

12.3K
The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
12.3K
Key Elements for Plant Nutrition02:35

Key Elements for Plant Nutrition

24.4K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
24.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gene-specific response to muscle specific kinase agonist antibody in the treatment of congenital myasthenic syndromes.

Brain communications·2026
Same author

Neuronal antenna senses signals from the bone to sustain cognition by boosting autophagy.

Autophagy·2025
Same author

A primary cilia-autophagy axis in hippocampal neurons is essential to maintain cognitive resilience.

Nature aging·2025
Same author

Cathelicidin antimicrobial peptide expression in neutrophils and neurons antagonistically modulates neuroinflammation.

The Journal of clinical investigation·2024
Same author

ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome.

Science translational medicine·2024
Same author

Agonist antibody to MuSK protects mice from MuSK myasthenia gravis.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same journal

[CREPT: An ally of immunotherapy for the fight against non-small-cell lung cancers].

Medecine sciences : M/S·2026
Same journal

[A new regulatory mechanism of HIF-1α: the ROS-ATM-CHK2 axis at the core of tumor angiogenesis].

Medecine sciences : M/S·2026
Same journal

[Vibrio-host interactions: from the environmental niche to virulence].

Medecine sciences : M/S·2026
Same journal

[RcsF, hyperconnected sentinel of the bacterial envelope].

Medecine sciences : M/S·2026
Same journal

[Single-cell RNA-sequencing: shattering the clone myth].

Medecine sciences : M/S·2026
Same journal

[No, Physarum blobs do not have 720 sexes!]

Medecine sciences : M/S·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
08:00

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

Published on: December 4, 2016

8.0K

[Osteocalcin, a key molecule for bone endocrine functions].

Julien Oury1, Franck Oury2

  • 1Center for biology and medicine, Skirball institute of biomolecular medicine, New York university medical school, New York, 10016, États-Unis.

Medecine Sciences : M/S
|February 1, 2018
PubMed
Summary
This summary is machine-generated.

The skeleton is a key endocrine organ, not just for structure. Osteocalcin (Ocn), a molecule from osteoclasts, plays crucial roles in whole-body homeostasis and physiological functions.

More Related Videos

Methods to Test Endocrine Disruption in Drosophila melanogaster
09:43

Methods to Test Endocrine Disruption in Drosophila melanogaster

Published on: July 3, 2019

10.4K
Models of Bone Metastasis
08:49

Models of Bone Metastasis

Published on: September 4, 2012

43.2K

Related Experiment Videos

Last Updated: Feb 15, 2026

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays
08:00

Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays

Published on: December 4, 2016

8.0K
Methods to Test Endocrine Disruption in Drosophila melanogaster
09:43

Methods to Test Endocrine Disruption in Drosophila melanogaster

Published on: July 3, 2019

10.4K
Models of Bone Metastasis
08:49

Models of Bone Metastasis

Published on: September 4, 2012

43.2K

Area of Science:

  • Endocrinology
  • Skeletal Biology
  • Physiology

Background:

  • The skeleton was historically viewed as a static structural tissue.
  • Recent research reveals the skeleton as a dynamic endocrine organ.
  • Inter-organ communication is vital for physiological functions and adaptation.

Purpose of the Study:

  • To review the endocrine roles of osteocalcin (Ocn).
  • To highlight the increasing functional importance of Ocn over the past 15 years.
  • To emphasize the skeleton's complex role in whole-body homeostasis.

Main Methods:

  • This review synthesizes findings from recent advances in mouse genetics.
  • It discusses signaling axes involving the skeletal system.
  • Focuses on the endocrine functions of osteocalcin.

Main Results:

  • The skeleton influences numerous physiological functions.
  • Osteocalcin (Ocn) is identified as a key molecule derived from osteoclasts.
  • Ocn's significance in endocrine regulation has grown substantially.

Conclusions:

  • The skeleton is a critical endocrine organ.
  • Osteocalcin (Ocn) has diverse and essential roles in maintaining bodily homeostasis.
  • Understanding the skeletal system's endocrine functions is crucial for holistic physiology.