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Updated: Feb 15, 2026

Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds
Published on: June 6, 2015
[Cell complexity should be placed at the heart of cancer research]
1Institut Curie, université de recherche Paris sciences et lettres (PSL), CNRS, UMR 144, 26, rue d'Ulm, 75248 Paris Cedex 05, France.
Abstract:
Genetic and most likely epigenetic alterations occurring during tumor progression and metastatic process lead to a broad deregulation of major cellular functions. However, the molecular mechanisms involved are still poorly understood. To understand them, the cell, the basic unit of life, remains more than ever the essential level to integrate the functional impact of genetics and epigenetics processes in the light of the global economy of the normal and cancerous cell, and of its interactions with its microenvironment.
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